Olivier Giroud’s opener, plus an Eden Hazard brace and strike from Pedro brought an end to a remarkable seven-year run for the Spaniard, in which he lifted the trophy in 2014, 2015 and 2016 with Sevilla.
Emery’s last exit from the tournament before Wednesday came at the hands of a 5-2 aggregate defeat by Atletico Madrid in the semi-finals of the 2011/2012 edition while boss of Valencia.
Unai Emery was knocked out of Europa League for first time since 2012 after Arsenal’s defeat
Emery would depart the club at the end of that season, moving to Spartak Moscow for a short-lived spell before returning to Spain with Sevilla in January 2013.
He would first lift the Europa League the following season, beating Maribor, Betis, Porto and Valencia in the knockout rounds on the way to overcoming Benfica on penalties in the final.
The Spaniard won the trophy for the first time in 2014 after his Sevilla side beat Benfica
Emery retained the trophy with the same club in 2015 by beating Dnipro Dnipropetrovsk
Sevilla would retain the trophy the following season, this time seeing off Borussia Monchengladbach, Villarreal, Zenit St Petersburg and Fiorentina before a 3-2 final win over Dnipro.
Although they qualified for the Champions League in 2015/2016, a third place in the group stage meant they once again went for Europa League glory.
Molde, Basel, Athletic Bilbao and Shakhtar Donetsk were all beaten before a 3-1 win over Liverpool secured a stunning third straight title for Emery and Sevilla.
Emery then moved on to coach PSG for two season, competing in the Champions League, but his move to Arsenal last season ensured another shot at winning the title that would fall at the last hurdle.
A third consecutive Europa League final victory would follow in 2016 by beating Liverpool 3-1